Okay. It took me this long to catch up. I'm surprised to be the first one responding! But I think that others started the book and couldn't put it down! I'm lucky that this book klub has progressed at a rate that I could still take part in some of these discussions.
Wow! What a ride these last few chapters have been! I love the direction the 'Noah's Ark' has taken. I only wish that there was a more literal way to translate...like 'flood' referred to the way the disease overwhelmed the people, or the ancient Hebrew word for flood also could be interpreted as 'pestilence' or something cool like that. I love the way specific versions of the Bible are quoted.
I wish there was a more descriptive way that the scientists were able to engineer the prion to only be infectious to humans. With the (lack of) knowledge that we have about prions, I think this technology would be a long way off. Or I could take it to mean that Garrett just has that much money and devotion to put into the research involved in the development of his humanity eliminator. Chilling.
I disagree with anyone who thinks the villain's plot is not believable. IMHO all it takes is one person with enough money and will to fulfill their crazy ideas. The really creepy thing about is that some of the things Garrett says I agree with: the potential of nuclear war, humanity being on the path to destroying all other life. We are all too lax in our vigilance against destroying the world that sustains us.
About prions: prion diseases are known to be very slow acting. I love it when authors use lesser known agents, which also helps inform or generate interest in something of which people would otherwise not be aware. I am hoping that later the story will explain how this particular prion is able to act so quickly. Maybe it is linked to why these prions degrade so fast. Also, people with certain genetics are more susceptible to prion diseases, and I would think that there would be a part of the population that would naturally be immune, as with other pathogenic organisms. I'm interested to see if this comes up in later in the book, although I would like it if Locke can stop everything in time so that this is a nonissue.
Cadherins--I'm very impressed with the use of this term. It wasn't even in my medical dictionary. I had to look it up in my Animal Cell Culture textbook to find out more about them. A section of my book says, "Epithelial cells are generally more resistant to disaggregation, as they tend to have tighter junctional complexes...holding them together, while mesenchymal cells, which are more dependent on matrix interactions for intercellular bonding, are more easily dissociated." This would mean that the people would dissolve from the inside out and would be a big sack of jelly before their skin would start to come apart, too. Yuck.
I love how well this book is written! I'm really glad that I bought all of your books, Boyd. I hope that you grow into a huge celebrity author, and I can tell people that I knew of you when...
Good times. I can't wait to read some more, but it is waaay past my bedtime and the dryer is beeping at me to fold some clothes! Until next week, all.
PS--I'm totally going to Orcas Island for my next vacation!
EDIT: I hope that I am not coming across as too critical of a great work of
fiction. I am just putting the things that are going through my head at the time of me reading the book out there.
